Bruce D. Roth

Synthetic studies toward verrucarol. 2. Synthesis of the AB ring system

George A. Kraus, Bruce D. Roth · The Journal of Organic Chemistry · 1980 · 247 citations

Natural Sciences, Biochemistry, Chemistry +5

Inhibitors of cholesterol biosynthesis. 3. Tetrahydro-4-hydroxy-6-[2-(1H-pyrrol-1-yl)ethyl]-2H-pyran 2-one inhibitors of HMG-CoA reductase. 2. Effects of introducing substituents at positions three and four of the pyrrole nucleus

Bruce D. Roth, C. John Blankley, Alexander Chucholowski et al. · Journal of Medicinal Chemistry · 1991 · 183 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-<i>tert</i>-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 1. Thiazolone and Oxazolone Series

Yuntao Song, David T. Connor, Robert Doubleday et al. · Journal of Medicinal Chemistry · 1999 · 130 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

The convergent synthesis of CI-981, an optically active, highly potent, tissue selective inhibitor of HMG-CoA reductase

Kelvin L. Baumann, Donald E. Butler, Carl F. Deering et al. · Tetrahedron Letters · 1992 · 123 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7

Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-<i>tert</i>-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 2. 1,3,4- and 1,2,4-Thiadiazole Series

Yuntao Song, David T. Connor, Anthony D. Sercel et al. · Journal of Medicinal Chemistry · 1999 · 120 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14