Donald E. Butler

The convergent synthesis of CI-981, an optically active, highly potent, tissue selective inhibitor of HMG-CoA reductase

Kelvin L. Baumann, Donald E. Butler, Carl F. Deering et al. · Tetrahedron Letters · 1992 · 121 citations

Aldo-keto Reductase, Novel Therapy, Biochemistry +8

The synthesis of (4R-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate, a key intermediate for the preparation of CI-981, a highly potent, tissue selective inhibitor of HMG-CoA reductase

Philip L. Brower, Donald E. Butler, Carl F. Deering et al. · Tetrahedron Letters · 1992 · 99 citations

Medicinal Chemistry, Key Intermediate, Aldo-keto Reductase +10

Amnesia-reversal activity of a series of cyclic imides

Donald E. Butler, James D. Leonard, Bradley W. Caprathe et al. · Journal of Medicinal Chemistry · 1987 · 66 citations

Cognition-activating properties of 3-(aryloxy)pyridines

Donald E. Butler, B. P. H. Poschel, John G. Marriott · Journal of Medicinal Chemistry · 1981 · 48 citations

Medicinal Chemistry, Cognitive Science, Neuropsychology +15

Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl]-2-oxo-1-pyrrolidineacetamides, including pramiracetam

Donald E. Butler, Ivan C. Nordin, Yvon J. L'Italien et al. · Journal of Medicinal Chemistry · 1984 · 47 citations

Bioorganic Chemistry, Organic Chemistry, Pharmacotherapy +19