Thomas Jensen

Design and Synthesis of Pyrrolo[2,3-<i>d</i>]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate

D.S. Williamson, Garrick P. Smith, Gitte Kobberøe Mikkelsen et al. · Journal of Medicinal Chemistry · 2021 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The identification of GPR3 inverse agonist AF64394; The first small molecule inhibitor of GPR3 receptor function

Thomas Jensen, Lisbeth Elster, Søren Nielsen et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 35 citations

Medicine, Medicinal Chemistry, Pharmacology +12

The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT3 receptor expressing interneurons: An in vitro study in rat hippocampus slices

Elena Dale, Morten Grunnet, Alan L. Pehrson et al. · Brain Research · 2017 · 30 citations

Life Sciences, Neuroscience, Pharmacology +17

Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain

Kenneth Thirstrup, Florence Sotty, Liliana Montezinho et al. · Pharmacological Research · 2015 · 28 citations

Medicine, Neurobiology, Neuroscience +7

Molecular cloning and pharmacological characterization of serotonin 5-HT3A receptor subtype in dog

Thomas Jensen, Jacob Nielsen, Kristen Frederiksen et al. · European Journal of Pharmacology · 2006 · 18 citations

Medicine, Neuroscience, Pharmacology +14