Garrick P. Smith

Discovery of 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): A Novel Multimodal Compound for the Treatment of Major Depressive Disorder

Benny Bang‐Andersen, Thomas Ruhland, Morten Jørgensen et al. · Journal of Medicinal Chemistry · 2011 · 589 citations · Full text

Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells

Kenneth Thirstrup, Justus C. Dächsel, Felix Oppermann et al. · Scientific Reports · 2017 · 101 citations · Full text

PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats

Michael Aagaard Andersen, Karen Malene Wegener, Steen Larsen et al. · Toxicology · 2018 · 69 citations · Full text

Non-adverse Renal Changes, Immunology, Cell Death +17

Asc-1 Transporter Regulation of Synaptic Activity via the Tonic Release of d-Serine in the Forebrain

Hagit Sason, Jean Marie Billard, Garrick P. Smith et al. · Cerebral Cortex · 2016 · 68 citations · Full text

D-serine Release, Synaptic Transmission, Neurotransmitter +19

Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive deficits in rats

John P. Redrobe, Lisbeth Elster, Kristen Frederiksen et al. · Psychopharmacology · 2011 · 56 citations

Gabaa α5 Receptors, Synaptic Plasticity, Cognitive Neuroscience +11