Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells.

Fortunato Ciardiello, Roberto Bianco, V. Damiano, +7

PubMed

Tumor BiologyOncologyAngiogenesisAntitumor ActivityGastrointestinal Oncology +11

Experimental emphysema induced with purified human neutrophil elastase: tissue localization of the instilled protease.

Aaron Janoff, Barbara Sloan, George Weinbaum, +4

PubMed

Inflammatory Lung DiseaseLung InflammationPmn ElastaseImmunologyPathology +18

A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients

Ferdinando De Vita, Michele Orditura, Elide Matano, +15

British Journal of Cancer

Gastrointestinal OncologyAdvanced Gastric CancerMedicineMetronomic TherapyPharmacology +10

Antitumor Activity of Combined Blockade of Epidermal Growth Factor Receptor and Protein Kinase A

Fortunato Ciardiello, V. Damiano, R. Bianco, +7

JNCI Journal of the National Cancer Institute

Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs

Roberto Bianco, Sonia Garofalo, Roberta Rosa, +6

British Journal of Cancer

Growth inhibition of human colon carcinoma cells by combinations of anti-epidermal growth factor-related growth factor antisense oligonucleotides.

Nicola Normanno, Cataldo Bianco, V. Damiano, +9

PubMed

Tumor BiologyOncologyGastrointestinal OncologyMedicineImmunology +13

Oral antisense that targets protein kinase A cooperates with taxol and inhibits tumor growth, angiogenesis, and growth factor production.

Giampaolo Tortora, Roberto Bianco, V. Damiano, +4

PubMed

Chemoprevention StrategyPkai Subunit RialphaInhibits Tumor GrowthCancer BiologyTumor Biology +16

Oral administration of a novel taxane, an antisense oligonucleotide targeting protein kinase A, and the epidermal growth factor receptor inhibitor Iressa causes cooperative antitumor and antiangiogenic activity.

Giampaolo Tortora, R. Caputo, V. Damiano, +6

PubMed

Gemcitabine combined with continuous infusion 5-fluorouracil in advanced and symptomatic pancreatic cancer: a clinical benefit-oriented phase II study

Elide Matano, P Tagliaferri, Annamaria Libroia, +4

British Journal of Cancer

Higher baseline TSH levels predict early hypothyroidism during cancer immunotherapy

Cristina Luongo, Rocco Morra, Carla Gambale, +7

Journal of Endocrinological Investigation