Toshio Kumagai

New C-4-chiral 1,3-thiazolidine-2-thiones: excellent chiral auxiliaries for highly diastereo-controlled aldol-type reactions of acetic acid and .alpha.,.beta.-unsaturated aldehydes

Yoshimitsu Nagao, Yuichi Hagiwara, Toshio Kumagai et al. · The Journal of Organic Chemistry · 1986 · 227 citations

Natural Sciences, Chemistry, Catalysis +9

Highly diastereoselective alkylation onto 4-acetoxy-2-azetidinones employing tin(II) enolates of 3-acyl C-4-chiral 1,3-thiazolidine-2-thiones

Yoshimitsu Nagao, Toshio Kumagai, Satoshi Tamai et al. · Journal of the American Chemical Society · 1986 · 78 citations

Natural Sciences, Chemistry, Catalysis +8

.beta.-Lactams. 3. Asymmetric total synthesis of new non-natural 1.beta.-methylcarbapenems exhibiting strong antimicrobial activities and stability against human renal dehydropeptidase-I

Yoshimitsu Nagao, Yunosuke Nagase, Toshio Kumagai et al. · The Journal of Organic Chemistry · 1992 · 67 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

Use of chiral 1,3-oxazolidine-2-thiones in the diastereoselective synthesis of aldols

Yoshimitsu Nagao, Shozo Yamada, Toshio Kumagai et al. · Journal of the Chemical Society Chemical Communications · 1985 · 63 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Novel efficient synthesis of 1-azabicyclo[1.1.0]butane and its application to the synthesis of 1-(1,3-thiazolin-2-yl)azetidine-3-thiol useful for the pendant moiety of an oral 1β-methylcarbapenem antibiotic L-084

Kazuhiko Hayashi, Chisato Sato, Shinsuke Hiki et al. · Tetrahedron Letters · 1999 · 53 citations

Pharmacy, Chemistry, Medicinal Chemistry +12