Shinsuke Hiki

Novel efficient synthesis of 1-azabicyclo[1.1.0]butane and its application to the synthesis of 1-(1,3-thiazolin-2-yl)azetidine-3-thiol useful for the pendant moiety of an oral 1β-methylcarbapenem antibiotic L-084

Kazuhiko Hayashi, Chisato Sato, Shinsuke Hiki et al. · Tetrahedron Letters · 1999 · 51 citations

Medicinal Chemistry, Diversity Oriented Synthesis, Heterocyclic +9

Synthesis of Azetidine Derivatives Using 1-Azabicyclo[1.1.0]butane

Yoshimitsu Nagao, Kazuhiko Hayashi, Shinsuke Hiki et al. · Heterocycles · 2002 · 33 citations · Full text

Derivatives, Heterocyclic, Thf Solution +6

2-(2-Phenylmorpholin-4-yl)pyrimidin-4(3H)-ones; A new class of potent, selective and orally active glycogen synthase kinase-3β inhibitors

Kenji Fukunaga, Fumiaki Uehara, Keiichi Aritomo et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 32 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +13

Discovery of novel 2-(3-phenylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors

Yoshihiro Usui, Fumiaki Uehara, Shinsuke Hiki et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 11 citations · Full text

Medicinal Chemistry, Medicine, Natural Sciences +5