Hiroki Kawasaki

T-614, a Novel Antirheumatic Drug, Inhibits Both the Activity and Induction of Cyclooxygenase-2 (COX-2) in Cultured Fibroblasts

Keiichi Tanaka, Hiroki Kawasaki, Kiyonobu Kurata et al. · The Japanese Journal of Pharmacology · 1995 · 76 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Pharmacological Studies on 3-Formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one (T-614), a Novel Antiinflammatory Agent. 4th Communication: Inhibitory Effect on the Production of Interleukin-1 and Interleukin-6.

Kéiichi Tanaka, Yukihiko Aikawa, Hiroki Kawasaki et al. · Journal of Pharmacobio-Dynamics · 1992 · 41 citations · Full text

Life Sciences, Medicinal Chemistry, Immunopharmacology +16

Human wee1 kinase is directly transactivated by and increased in association with c-Fos/AP-1: rheumatoid synovial cells overexpressing these genes go into aberrant mitosis

Hiroki Kawasaki, Koichiro Komai, Mikiko Nakamura et al. · Oncogene · 2003 · 29 citations

Life Sciences, Cell Biology, Genetics +16

p21waf1/cip1 is down-regulated in conjunction with up-regulation of c-Fos in the lymphocytes of rheumatoid arthritis patients

M Hikasa, Eri Yamamoto, Hiroki Kawasaki et al. · Biochemical and Biophysical Research Communications · 2003 · 11 citations

Life Sciences, Immunology, Molecular Biology +9

Heat shock protein 90 is required for increased DNA binding activity of activator protein-1, a heterodimer of Fos/JunD, in rheumatoid synovial cells under inflammatory stimuli

Miki Murata, Yasushi Miura, Akira Hashiramoto et al. · International Journal of Molecular Medicine · 2005 · 11 citations

Medicine, Immunology, Molecular Biology +17