M Sekiguchi

O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis.

Yoko Nakatsuru, Susumu Matsukuma, Nobuo Nemoto et al. · Proceedings of the National Academy of Sciences · 1993 · 144 citations

Medicine, Genetics, Molecular Biology +17

Methylnitrosourea-induced tumorigenesis in MGMT gene knockout mice.

Kunihiko Sakumi, Akira Shiraishi, Seiichiro Shimizu et al. · PubMed · 1997 · 133 citations

Medicine, Genetics, Oncology +12

A specific role of MutT protein: to prevent dG.dA mispairing in DNA replication.

Masahiro Akiyama, Harufumi Maki, M Sekiguchi et al. · Proceedings of the National Academy of Sciences · 1989 · 120 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Cyclin-dependent kinase-like 5 binds and phosphorylates DNA methyltransferase 1

Isamu Kameshita, M Sekiguchi, Daisuke Hamasaki et al. · Biochemical and Biophysical Research Communications · 2008 · 95 citations

Life Sciences, Cell Biology, Molecular Biology +10

Purification, structure, and biochemical properties of human O6-methylguanine-DNA methyltransferase.

George Koike, Harufumi Maki, Hiroyuki Takeya et al. · Journal of Biological Chemistry · 1990 · 84 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13