Ariel Talavera

Nimotuzumab, an Antitumor Antibody that Targets the Epidermal Growth Factor Receptor, Blocks Ligand Binding while Permitting the Active Receptor Conformation

Ariel Talavera, Rosmarie Friemann, Silvia Gómez-Puerta et al. · Cancer Research · 2009 · 196 citations

Medicine, Oncology, Pharmacology +17

Direct activation of a bacterial innate immune system by a viral capsid protein

Tong Zhang, Hedvig Tamman, Kyo Coppieters ’t Wallant et al. · Nature · 2022 · 195 citations · Full text

Life Sciences, Immunology, Microbiology +17

Mouse TRPA1 function and membrane localization are modulated by direct interactions with cholesterol

Justyna B. Startek, Brett Boonen, Alejandro López‐Requena et al. · eLife · 2019 · 72 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes

Hedvig Tamman, Katleen Van Nerom, Hiraku Takada et al. · Nature Chemical Biology · 2020 · 49 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

(p)ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains

Mohammad Roghanian, Katleen Van Nerom, Hiraku Takada et al. · Molecular Cell · 2021 · 48 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17