Kenta Hashizume

Comprehensive PBPK Model of Rifampicin for Quantitative Prediction of Complex Drug‐Drug Interactions: CYP3A/2C9 Induction and OATP Inhibition Effects

Ryuta Asaumi, Kota Toshimoto, Yoshifusa Tobe et al. · CPT Pharmacometrics & Systems Pharmacology · 2018 · 57 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

<i>In vitro</i>studies with two human organic anion transporters: OAT2 and OAT7

Sumathy Mathialagan, Chester Costales, Laurie Tylaska et al. · Xenobiotica · 2017 · 23 citations

Medicine, Biochemistry, Pharmacology +15

Strategies to improve the prediction accuracy of hepatic intrinsic clearance of three antidiabetic drugs: Application of the extended clearance concept and consideration of the effect of albumin on CYP2C metabolism and OATP1B-mediated hepatic uptake

Ryo Fujino, Kenta Hashizume, Shinsuke Aoyama et al. · European Journal of Pharmaceutical Sciences · 2018 · 19 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Antitubercular Agent Delamanid and Metabolites as Substrates and Inhibitors of ABC and Solute Carrier Transporters

Hiroyuki Sasabe, Yoshihiko Shimokawa, Masakazu SHIBATA et al. · Antimicrobial Agents and Chemotherapy · 2016 · 15 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

<i>In vitro</i> evaluations for pharmacokinetic drug-drug interactions of a novel serotonin-dopamine activity modulator, brexpiprazole

Hiroyuki Sasabe, Toshihisa Koga, Masayuki Furukawa et al. · Xenobiotica · 2021 · 15 citations

Pharmacy, Pharmacokinetics, Pharmacology +17