Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

Stefan M. Gehrig, Chris van der Poel, Timothy A. Sayer, +8

Nature

Muscle FunctionMolecular PhysiologyMuscle InjurySkeletal MuscleMedicine +5

Defective lysosome reformation during autophagy causes skeletal muscle disease

Meagan J. McGrath, Matthew J. Eramo, Rajendra Gurung, +9

Journal of Clinical Investigation

MitophagyLysosomal HomeostasisCytoskeletonCellular PhysiologyCell Autophagy +17

Making Fast-Twitch Dystrophic Muscles Bigger Protects Them from Contraction Injury and Attenuates the Dystrophic Pathology

Stefan M. Gehrig, René Koopman, Timur Naim, +2

American Journal Of Pathology

Contraction InjuryMuscle FunctionKinesiologyMuscle InjurySkeletal Muscle +6

Cellular mechanisms underlying temporal changes in skeletal muscle protein synthesis and breakdown during chronic β-adrenoceptor stimulation in mice

René Koopman, Stefan M. Gehrig, Bertrand Léger, +4

The Journal of Physiology

Muscle FunctionCellular PhysiologyChronic β-Adrenoceptor StimulationChronic StimulationMolecular Pharmacology +17

Dysfunctional Muscle and Liver Glycogen Metabolism in mdx Dystrophic Mice

David Stapleton, Xianzhong Lau, Marcelo Flores‐Opazo, +6

PLoS ONE

Modulation of Insulin-like Growth Factor (IGF)-I and IGF-Binding Protein Interactions Enhances Skeletal Muscle Regeneration and Ameliorates the Dystrophic Pathology in mdx Mice

Jonathan D. Schertzer, Stefan M. Gehrig, James G. Ryall, +1

American Journal Of Pathology

Regenerative MedicineGrowth HormoneMdx MiceInsulin-like Growth FactorHuman Growth +6

Insulin‐like growth factor‐I analogue protects muscles of dystrophic <i>mdx</i> mice from contraction‐mediated damage

Stefan M. Gehrig, James G. Ryall, Jonathan D. Schertzer, +1

Experimental Physiology

Muscle FunctionContraction-mediated InjuryInsulin SignalingCellular PhysiologyIgf-i Signalling +15

Intramuscular β₂-agonist administration enhances early regeneration and functional repair in rat skeletal muscle after myotoxic injury

James G. Ryall, Jonathan D. Schertzer, Tammy M. Alabakis, +3

Journal of Applied Physiology

HypertensionHeart FailureMuscle FunctionMyotoxic InjuryEarly Regeneration +18

BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle

Tahnee L. Kennedy, Kristy Swiderski, Kate T. Murphy, +7

American Journal Of Pathology

Metabolic SyndromeCardiomyopathySkeletal MusclePhysiologyDegenerative Disease +7

Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity

Justin P. Hardee, Karen Janet Bernice Martins, Paula M. Miotto, +14

Molecular Metabolism