Leon A. G. M. van den Broek

Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis

Terry D. Butters, Leon A. G. M. van den Broek, George W. J. Fleet et al. · Tetrahedron Asymmetry · 2000 · 142 citations

Life Sciences, Biochemistry, Molecular Biology +16

Chemical modification of azasugars, inhibitors of N‐glycoprotein‐processing glycosidases and of HIV‐I infection: Review and structure‐activity relationships

Leon A. G. M. van den Broek, D. J. Vermaas, B. M. Heskamp et al. · Recueil des Travaux Chimiques des Pays-Bas · 1993 · 67 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

1,3-Dipolar cycloaddition reactions of homochiral cyclic nitrones derived from 1-deoxynojirimycin

Leon A. G. M. van den Broek · Tetrahedron · 1996 · 43 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Structure-activity relationships of sparsomycin and its analogs. Inhibition of peptide bond formation in cell-free systems and of L1210 and bacterial cell growth

Leon A. G. M. van den Broek, Rob M. J. Liskamp, J. H. COLSTEE et al. · Journal of Medicinal Chemistry · 1987 · 34 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Lipophilic analogs of sparsomycin as strong inhibitors of protein synthesis and tumor growth: a structure-activity relationship study

Leon A. G. M. van den Broek, Ester Lázaro, Zbigniew Żylicz et al. · Journal of Medicinal Chemistry · 1989 · 34 citations

Medicine, Medicinal Chemistry, Pharmacology +9