Paul Heller

5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β⁺Thalassemia

Timothy J. Ley, Joseph DeSimone, Nicholas P. Anagnou et al. · New England Journal of Medicine · 1982 · 493 citations

5-Azacytidine Selectivity, Bone Marrow Failure, Biochemistry +10

5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons.

J DeSimone, Paul Heller, L Hall et al. · Proceedings of the National Academy of Sciences · 1982 · 393 citations · Full text

Hb F, Heme Homeostasis, Medicine +14

5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia

TJ Ley, Joseph DeSimone, CT Noguchi et al. · Blood · 1983 · 253 citations · Full text

Clinical Implications of Sickle-Cell Trait and Glucose-6-Phosphate Dehydrogenase Deficiency in Hospitalized Black Male Patients

Paul Heller, William R. Best, Rodney B. Nelson et al. · New England Journal of Medicine · 1979 · 167 citations

Immunohematology, Thrombosis, Clinical Implications +12

Stimulation of fetal hemoglobin synthesis in baboons by hemolysis and hypoxia.

Joseph DeSimone, Stephanie Biel, Paul Heller · Proceedings of the National Academy of Sciences · 1978 · 93 citations · Full text

Animal Physiology, Developmental Biology, Hb F +14