Patricia R. Jennings

Peroxisomal alanine:glyoxylate aminotransferase deficiency in primary hyperoxaluria type I

Christopher J. Danpure, Patricia R. Jennings · FEBS Letters · 1986 · 347 citations

Life Sciences, Biochemistry, Biochemical Genetics +16

An enzyme trafficking defect in two patients with primary hyperoxaluria type 1: peroxisomal alanine/glyoxylate aminotransferase rerouted to mitochondria.

Christopher J. Danpure, P. J. Cooper, P. J. Wise et al. · The Journal of Cell Biology · 1989 · 164 citations · Full text

Life Sciences, Biochemistry, Pathobiology +16

Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeting of AGT in primary hyperoxaluria type 1.

Alison M. Motley, Michael J. Lumb, Paru B. Oatey et al. · The Journal of Cell Biology · 1995 · 91 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Enzymological and mutational analysis of a complex primary hyperoxaluria type 1 phenotype involving alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting and intraperoxisomal aggregation.

Christopher J. Danpure, P. Edward Purdue, P Fryer et al. · PubMed · 1993 · 86 citations

Life Sciences, Biochemistry, Molecular Biology +17

Subcellular distribution of hepatic alanine:glyoxylate aminotransferase in various mammalian species

Christopher J. Danpure, K. M. Guttridge, P Fryer et al. · Journal of Cell Science · 1990 · 71 citations

Life Sciences, Biochemistry, Molecular Biology +17