Michael J. Lumb - Concepedia

Author

Michael J. Lumb

University College London

Also Known As

M J Lumb, MICHAEL J. LUMB, Michael J Lumb, Michael J. LUMB, Michael J. Lumb

Publications

1.4K

Citations

H-Index

Concepts

All Affiliations

University College London MRC Laboratory for Molecular Cell Biology Tufts University Medical Research Council University at Buffalo, State University of New York

About

Michael J. Lumb is an author at University College London specializing in medicine, biochemistry, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	8	8	729
2	Biochemistry	6	6	374
3	Natural Sciences	4	4	269
4	Social Sciences	3	3	163
5	Cell Biology	3	3	365

Michael J. Lumb

Publications

1.3K

Citations

H-Index

Page 1

	Year	Citations
Delivery of GABAARs to Synapses Is Mediated by HAP1-KIF5 and Disrupted by Mutant Huntingtin Alison E. Twelvetrees, Eunice Y. Yuen, I. Lorena Arancibia‐Cárcamo, Neuron Synaptic PlasticitySignal TransductionMolecular NeuroscienceSynaptic TransmissionNeurotransmitter	2010	258
Functional Synergism between the Most Common Polymorphism in Human Alanine:Glyoxylate Aminotransferase and Four of the Most Common Disease-causing Mutations Michael J. Lumb, Christopher J. Danpure Journal of Biological Chemistry	2000	138
Characterization and chromosomal mapping of a genomic clone encoding human alanine:Glyoxylate aminotransferase P. Edward Purdue, Michael J. Lumb, Margaret Fox, Genomics Genomic CloneBiochemistryChromosomal MappingGeneticsNatural Sciences	1991	135
Benzodiazepines Modulate GABA<sub>A</sub>Receptors by Regulating the Preactivation Step after GABA Binding Marc Gielen, Michael J. Lumb, Trevor G. Smart Journal of Neuroscience	2012	108
Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeting of AGT in primary hyperoxaluria type 1. Alison M. Motley, Michael J. Lumb, Paru B. Oatey, The Journal of Cell Biology Mammalian Pts1 MotifGeneticsMolecular BiologyAmino Acid SubstitutionAmino Acid Substitutions	1995	90
Ubiquitin-dependent lysosomal targeting of GABA <sub>A</sub> receptors regulates neuronal inhibition I. Lorena Arancibia‐Cárcamo, Eunice Y. Yuen, James Muir, Proceedings of the National Academy of Sciences Surface GabaSynaptic TransmissionNeurotransmitterSynaptic GabaNeurotransmission	2009	87
Enzymological and mutational analysis of a complex primary hyperoxaluria type 1 phenotype involving alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting and intraperoxisomal aggregation. Christopher J. Danpure, P. Edward Purdue, P Fryer, PubMed	1993	86
Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged γ-Aminobutyric Acid Receptor, Type A (GABAA), α2 Subunit Knock-in Mouse Yasuko Nakamura, Danielle Morrow, Amit Modgil, Journal of Biological Chemistry Synaptic PlasticityProteomic CharacterizationSignal TransductionMolecular NeuroscienceBiochemistry	2016	56
Molecular evolution of alanine/glyoxylate aminotransferase 1 intracellular trageting P. Edward Purdue, Michael J. Lumb, Christopher J. Danpure European Journal of Biochemistry	1992	50
A glycine-to-glutamate substitution abolishes alanine:glyoxylate aminotransferase catalytic activity in a subset of patients with primary hyperoxaluria type 1 P. Edward Purdue, Michael J. Lumb, Jennifer Allsop, Genomics Primary HyperoxaluriaBiochemistryMedicineInherited Metabolic DiseaseRenal Pathophysiology	1992	49

Page 1