Zong Ru Guo

Comparison of the inhibition of methotrexate-sensitive and -resistant Lactobacillus casei cell cultures with purified Lactobacillus casei dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-substituted-phenyl)-s-triazines. Use of quantitative structure-activity relationships in making inferences about the mechanism of resistance and the structure of the enzyme in situ compared with the enzyme in vitro

Eugene A. Coats, Clara S. Genther, Stephen W. Dietrich et al. · Journal of Medicinal Chemistry · 1981 · 18 citations · Full text

Inhibition of human dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(substituted-phenyl)-s-triazines. A quantitative structure-activity relationship analysis

Bruce A. Hathaway, Zong Ru Guo, Corwin Hansch et al. · Journal of Medicinal Chemistry · 1984 · 17 citations · Full text

A comparison of the inhibition of growth of methotrexate-resistant and -sensitive leukemia cells in culture by triazines. Evidence for a new mechanism of cell resistance to methotrexate

Cynthia Dias Selassie, Zong Ru Guo, Corwin Hansch et al. · Journal of Medicinal Chemistry · 1982 · 10 citations

Comparison of quantitative structure-activity relationships of the inhibition of leukemia cells in culture with the inhibition of dihydrofolate reductase from leukemia cells and other cell types

Tasneem A. Khwaja, Stephanie Pentecost, Cynthia Dias Selassie et al. · Journal of Medicinal Chemistry · 1982 · 10 citations

Bioorganic Chemistry, Chemoprevention Strategy, Aldo-keto Reductase +19