A E Pegg

Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.

M. Eileen Dolan, R. Brian Mitchell, Christine Mummert et al. · PubMed · 1991 · 228 citations

Medicine, Oncology, Pharmacology +5

Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma.

H. S. Friedman, Demetrius M. Kokkinakis, James M. Pluda et al. · Journal of Clinical Oncology · 1998 · 217 citations · Full text

Medicine, Oncology, Pharmacology +16

Activity of temozolomide in the treatment of central nervous system tumor xenografts.

Henry S. Friedman, M E Dolan, A E Pegg et al. · PubMed · 1995 · 142 citations

Medicine, Oncology, Pharmacology +15

Effect of androgens on turnover of ornithine decarboxylase in mouse kidney. Studies using labeling of the enzyme by reaction with [14C] alpha-difluoromethylornithine.

James E. Seely, Hannu Pösö, A E Pegg · Journal of Biological Chemistry · 1982 · 139 citations · Full text

Life Sciences, Biochemistry, Endocrinology +16

Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide.

Demetrius M. Kokkinakis, Dora Bocangel, S. Clifford Schold et al. · PubMed · 2001 · 75 citations

Medicine, Oncology, Pharmacology +17