Concepedia

David Filpula

DF

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Publications

22

Citations

3.1K

H-Index

20

Active since

1983

Affiliations

Enzon Pharmaceuticals (United States)(Current)

Genex Systems (United States)

National Institutes of Health

National Cancer Institute

David Filpula is an author at Enzon Pharmaceuticals (United States) specializing in life sciences, protein engineering, and molecular biology.

Publications per year

1983–2008

22

Publications

22

A Novel, Highly Stable Fold of the Immunoglobulin Binding Domain of Streptococcal Protein G

Angela M. Gronenborn, David Filpula, Nina Z. Essig et al. · Science · 1991 · 826 citations

, , +17

Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49.

Diane E. Milenic, Takashi Yokota, David Filpula et al. · PubMed · 1991 · 340 citations

, , +17

An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability

M. Whitlow, Brian Bell, Sheau-Line Feng et al. · Protein Engineering Design and Selection · 1993 · 311 citations

, , +12

A RNA antagonist of hypoxia-inducible factor-1α, EZN-2968, inhibits tumor cell growth

Lee M. Greenberger, Ivan D. Horak, David Filpula et al. · Molecular Cancer Therapeutics · 2008 · 242 citations · Full text

, , +16

Structure−Function Engineering of Interferon-β-1b for Improving Stability, Solubility, Potency, Immunogenicity, and Pharmacokinetic Properties by Site-Selective Mono-PEGylation

Amartya Basu, Karen Yang, Maoliang Wang et al. · Bioconjugate Chemistry · 2006 · 214 citations

, , +17

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