Akinari Hidaka

Mutation of alanine 623 in the third cytoplasmic loop of the rat thyrotropin (TSH) receptor results in a loss in the phosphoinositide but not cAMP signal induced by TSH and receptor autoantibodies.

Shinji Kosugi, Fumikazu Okajima, T Ban et al. · Journal of Biological Chemistry · 1992 · 130 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

A new constitutively activating point mutation in the luteinizing hormone/choriogonadotropin receptor gene in cases of male-limited precocious puberty.

Koichi Yano, Motoyasu Saji, Akinari Hidaka et al. · The Journal of Clinical Endocrinology & Metabolism · 1995 · 84 citations

Medicine, Endocrinology, Genetics +17

Serum CA 19-9 concentrations and computed tomography findings in patients with pancreatic carcinoma

Harumi Sakahara, Keigo Endo, Kotoko NAKAJIMA et al. · Cancer · 1986 · 70 citations

Medicine, Oncology, Pathology +13

Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.

Shinji Kosugi, Fumikazu Okajima, T Ban et al. · Molecular Endocrinology · 1993 · 68 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

A sporadic case of male-limited precocious puberty has the same constitutively activating point mutation in luteinizing hormone/choriogonadotropin receptor gene as familial cases.

Koichi Yano, Akinari Hidaka, Motoyasu Saji et al. · The Journal of Clinical Endocrinology & Metabolism · 1994 · 66 citations

Life Sciences, Endocrinology, Genetics +14