T Ban

Mutation of alanine 623 in the third cytoplasmic loop of the rat thyrotropin (TSH) receptor results in a loss in the phosphoinositide but not cAMP signal induced by TSH and receptor autoantibodies.

Shinji Kosugi, Fumikazu Okajima, T Ban et al. · Journal of Biological Chemistry · 1992 · 130 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Site-directed mutagenesis of a portion of the extracellular domain of the rat thyrotropin receptor important in autoimmune thyroid disease and nonhomologous with gonadotropin receptors. Relationship of functional and immunogenic domains.

Shinji Kosugi, T Ban, Takashi Akamizu et al. · Journal of Biological Chemistry · 1991 · 105 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropin receptors.

Shinji Kosugi, T Ban, Takashi Akamizu et al. · Molecular Endocrinology · 1992 · 82 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Major histocompatibility complex class I gene expression in rat thyroid cells is regulated by hormones, methimazole, and iodide as well as interferon.

Motoyasu Saji, John Moriarty, T Ban et al. · The Journal of Clinical Endocrinology & Metabolism · 1992 · 75 citations

Life Sciences, Endocrinology, Molecular Biology +15

Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.

Shinji Kosugi, Fumikazu Okajima, T Ban et al. · Molecular Endocrinology · 1993 · 68 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17