Agnès Vidal

Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH)

David C. Tully, Paul V. Rucker, D. CHIANELLI et al. · Journal of Medicinal Chemistry · 2017 · 230 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery, Optimization, and Biological Evaluation of 5-(2-(Trifluoromethyl)phenyl)indazoles as a Novel Class of Transient Receptor Potential A1 (TRPA1) Antagonists

Lisa Rooney, Agnès Vidal, Anne-Marie D’Souza et al. · Journal of Medicinal Chemistry · 2014 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Solid-Phase Synthesis of α,α-Difluoro-β-amino Acids via the Reformatsky Reaction

Agnès Vidal, Adel Nefzi, Richard A. Houghten · The Journal of Organic Chemistry · 2001 · 36 citations

Natural Sciences, Biochemistry, Chemistry +10

Solid-Phase Synthesis of 1,2,5-Trisubstituted 4-Imidazolidinones

Markéta Rinnová, Agnès Vidal, Adel Nefzi et al. · Journal of Combinatorial Chemistry · 2002 · 22 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design

David C. Tully, Agnès Vidal, Arnab K. Chatterjee et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 20 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +12