Altered Pharmacokinetics of 1α,25-Dihydroxyvitamin D₃and 25-Hydroxyvitamin D₃in the Blood and Tissues of the 25-Hydroxyvitamin D-24-Hydroxylase (<i>Cyp24a1</i>) Null Mouse

Sonoko Masuda, Valarie Byford, Alice Arabian, +4

Endocrinology

Vitamin D HomeostasisAltered PharmacokineticsBiochemistry25-Hydroxyvitamin D-24-hydroxylaseMedicine +12

Regulatory activities of 2β-(3-hydroxypropoxy)-1α,25-dihydroxyvitamin D3, a novel synthetic vitamin D3 derivative, on calcium metabolism

Toshio Okano, Naoko Tsugawa, Sonoko Masuda, +4

Biochemical and Biophysical Research Communications

BiochemistryMedicinePhysiologyRegulatory ActivitiesMetabolism +2

Protein-binding properties of 22-oxa-1.ALPHA.,25-dihydroxyvitamin D3, a synthetic analogue of 1.ALPHA.,25-dyhydroxyvitamin D3.

Toshio Okano, Naoko Tsugawa, Sonoko Masuda, +3

Journal of Nutritional Science and Vitaminology

Chemical BiologyNutrient PhysiologyBiochemistryVitamin D3Medicine +10

The Binding Properties, with Blood Proteins, and Tissue Distribution of 22-Oxa-1α, 25-Dihydroxyvitamin D3, a Noncalcemic Analogue of 1α, 25-Dihydroxyvitamin D3, in Rats1

Tadashi Kobayashi, Naoko Tsugawa, Toshio Okano, +4

The Journal of Biochemistry

Concentrations of vitamin D-binding protein and vitamin D metabolites in plasma of patients with liver cirrhosis.

Sonoko Masuda, Toshio Okano, K Osawa, +3

Journal of Nutritional Science and Vitaminology

NutritionLiver CirrhosisFatty Liver DiseasePlasma LevelsHepatotoxicity +16

In Vitro Metabolism of the Vitamin D Analog, 22-Oxacalcitriol, Using Cultured Osteosarcoma, Hepatoma, and Keratinocyte Cell Lines

Sonoko Masuda, Valarie Byford, Richard Kremer, +7

Journal of Biological Chemistry

Characterization of 3-Epi-1.ALPHA.,25-dihydroxyvitamin D3 Involved in 1.ALPHA.,25-Dihydroxyvitamin D3 Metabolic Pathway in Cultured Cell Lines.

Sonoko Masuda, Maya Kamao, Neil J. Schroeder, +5

Biological and Pharmaceutical Bulletin

Generation of a homology model for the human cytochrome P450, CYP24A1, and the testing of putative substrate binding residues by site-directed mutagenesis and enzyme activity studies

Sonoko Masuda, David E. Prosser, Yu-Ding Guo, +2

Archives of Biochemistry and Biophysics

Cellular EnzymologyBiochemistryNatural SciencesMolecular BiologyHuman Cytochrome P450 +5

A novel high-performance liquid chromatographic assay for vitamin D metabolites using a coulometric electrochemical detector

Sonoko Masuda, Toshio Okano, Maya Kamao, +2

Journal of Pharmaceutical and Biomedical Analysis

BiochemistryGas ChromatographyMedicineBioanalysisMass Spectrometry +9

Hepatic activation and inactivation of clinically-relevant vitamin D analogs and prodrugs.

Glenville Jones, Valarie Byford, Shelly West, +6

PubMed

HepatologyBiochemistryMedicineLiver PhysiologyNatural Sciences +13