T. D. Southgate

Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for clinical trials

Ricardo A. Dewey, Graham Morrissey, Christine M. Cowsill et al. · Nature Medicine · 1999 · 314 citations

Medicine, Neuroscience, Oncology +15

Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity.

Adrián E. Morelli, Adriana T. Larregina, Joseph R. Smith-Arica et al. · Journal of General Virology · 1999 · 107 citations

Life Sciences, Biotechnology, Molecular Biology +16

Interleukin-1 Mediates a Rapid Inflammatory Response After Injection of Adenoviral Vectors into the Brain

Tammy Cartmell, T. D. Southgate, Gwen S. Rees et al. · Journal of Neuroscience · 1999 · 106 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Transcriptional Targeting to Anterior Pituitary Lactotrophic Cells Using Recombinant Adenovirus Vectors in Vitro and in Vivo in Normal and Estrogen/Sulpiride-Induced Hyperplasic Anterior Pituitaries*

T. D. Southgate, S. Windeatt, Joseph R. Smith-Arica et al. · Endocrinology · 2000 · 68 citations

Life Sciences, Biotechnology, Molecular Biology +15

Human monocytes expressing a CEA-specific chimeric CD64 receptor specifically target CEA-expressing tumour cells in vitro and in vivo

Alireza Biglari, T. D. Southgate, LJ Fairbairn et al. · Gene Therapy · 2006 · 67 citations

Medicine, Immunology, Oncology +11