Luca Caruana

Insulin Resistance as Common Molecular Denominator Linking Obesity to Alzheimer’s Disease

Domenico Nuzzo, Pasquale Picone, Sara Baldassano et al. · Current Alzheimer Research · 2015 · 117 citations

Metformin increases APP expression and processing via oxidative stress, mitochondrial dysfunction and NF-κB activation: Use of insulin to attenuate metformin's effect

Pasquale Picone, Domenico Nuzzo, Luca Caruana et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2015 · 112 citations · Full text

Inflammation, Biochemistry, Mitochondrial Dysfunction +12

Biological and biophysics aspects of metformin-induced effects: cortex mitochondrial dysfunction and promotion of toxic amyloid pre-fibrillar aggregates

Pasquale Picone, Silvia Vilasi, Fabio Librizzi et al. · Aging · 2016 · 60 citations · Full text

Curcumin induces apoptosis in human neuroblastoma cells via inhibition of AKT and Foxo3a nuclear translocation

Pasquale Picone, Domenico Nuzzo, Luca Caruana et al. · Free Radical Research · 2014 · 44 citations

Chemoprevention Strategy, Apoptosis, Cell Death +17

Altered insulin pathway compromises mitochondrial function and quality control both in in vitro and in vivo model systems

Giacoma Galizzi, Laura Palumbo, Antonella Amato et al. · Mitochondrion · 2021 · 24 citations · Full text

Metabolic Syndrome, Systems Biology, Biochemistry +11