Iwona Szymkiewicz

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

Kaisa Haglund, Sara Sigismund, Simona Polo et al. · Nature Cell Biology · 2003 · 792 citations

Multiple Monoubiquitination, Receptor Tyrosine Kinase, Pathogenesis +6

Cbl–CIN85–endophilin complex mediates ligand-induced downregulation of EGF receptors

Philippe Soubeyran, Katarzyna Kowanetz, Iwona Szymkiewicz et al. · Nature · 2002 · 568 citations

Signal Transduction, Signaling Pathway, Egf Receptors +4

Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors

Kaisa Haglund, Noriaki Shimokawa, Iwona Szymkiewicz · Proceedings of the National Academy of Sciences · 2002 · 152 citations

Ligand-induced Degradation, Molecular Regulation, Cellular Physiology +16

CIN85 Participates in Cbl-b-mediated Down-regulation of Receptor Tyrosine Kinases

Iwona Szymkiewicz, Katarzyna Kowanetz, Philippe Soubeyran et al. · Journal of Biological Chemistry · 2002 · 135 citations · Full text

Identification of a Novel Proline-Arginine Motif Involved in CIN85-dependent Clustering of Cbl and Down-regulation of Epidermal Growth Factor Receptors

Katarzyna Kowanetz, Iwona Szymkiewicz, Kaisa Haglund et al. · Journal of Biological Chemistry · 2003 · 129 citations · Full text