A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta

Christopher Whidbey, Maria I. Harrell, Kellie Burnside, +7

The Journal of Experimental Medicine

Bacterial PenetrationMedical MicrobiologyHuman PlacentaAmniotic FluidMedicine +10

Uterine overdistention induces preterm labor mediated by inflammation: observations in pregnant women and nonhuman primates

Kristina M. Adams Waldorf, Natasha Singh, Aarthi Mohan, +17

American Journal of Obstetrics and Gynecology

Postpartum HemorrhagePreterm LaborMaternal ComplicationReproductive HealthUterine Overdistention Induces +10

Group B <i>Streptococcus</i> circumvents neutrophils and neutrophil extracellular traps during amniotic cavity invasion and preterm labor

Erica Boldenow, Claire Gendrin, Lisa Ngo, +17

Science Immunology

A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury

Christopher Whidbey, Jay Vornhagen, Claire Gendrin, +11

EMBO Molecular Medicine

Mast cell degranulation by a hemolytic lipid toxin decreases GBS colonization and infection

Claire Gendrin, Jay Vornhagen, Lisa Ngo, +9

Science Advances

Comparative Effects of Glucose-Lowering Medications on Kidney Outcomes in Type 2 Diabetes

Deborah J. Wexler, Ian H. de Boer, Alokananda Ghosh, +517

JAMA Internal Medicine

Optimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight

William I. Sivitz, Lawrence S. Phillips, Deborah J. Wexler, +473

Diabetes Care

Association of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort

Neda Rasouli, Naji Younes, Kristina M. Utzschneider, +471

Diabetes Care

Diminished Capsule Exacerbates Virulence, Blood–Brain Barrier Penetration, Intracellular Persistence, and Antibiotic Evasion of Hyperhemolytic Group B Streptococci

Claire Gendrin, Sean Merillat, Jay Vornhagen, +7

The Journal of Infectious Diseases

Longitudinal Effects of Glucose-Lowering Medications on β-Cell Responses and Insulin Sensitivity in Type 2 Diabetes: The GRADE Randomized Clinical Trial

Neda Rasouli, Naji Younes, Alokananda Ghosh, +522

Diabetes Care