Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer

Clara Montagut, Alba Dalmases, Beatríz Bellosillo, +16

Nature Medicine

Extracellular DomainMedicineColorectal CancerCancer GenomicsCetuximab Resistance +5

Chemoradiation, surgery and adjuvant chemotherapy versus induction chemotherapy followed by chemoradiation and surgery: long-term results of the Spanish GCR-3 phase II randomized trial

Carlos Fernández-Martos, Xabier García‐Albéniz, Carles Pericay, +12

Annals of Oncology

Surgical OncologyRadiation TherapyMedicineBreast CancerSurgery +4

Immunohistochemical Staining for p16 and p53 in Premalignant and Malignant Epithelial Lesions of the Vulva

Mônica Santos, Clara Montagut, Begoña Mellado, +5

International Journal of Gynecological Pathology

Preoperative Chemotherapy in Patients With Intermediate-Risk Rectal Adenocarcinoma Selected by High-Resolution Magnetic Resonance Imaging: The GEMCAD 0801 Phase II Multicenter Trial

Carlos Fernández-Martos, Gina Brown, Rafael Estevan, +17

The Oncologist

Tyrosinase mRNA in Blood of Patients With Melanoma Treated With Adjuvant Interferon

Begoña Mellado, María Vela, Dolors Colomer, +8

Journal of Clinical Oncology

FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer

Laetitia Marzi, Eve Combès, Nadia Vié, +14

British Journal of Cancer

The McCAVE Trial: Vanucizumab plus mFOLFOX-6 Versus Bevacizumab plus mFOLFOX-6 in Patients with Previously Untreated Metastatic Colorectal Carcinoma (mCRC)

Johanna C. Bendell, Tamara Saurí, Antonio Cubillo Gracián, +23

The Oncologist

Multi-Center Evaluation of the Fully Automated PCR-Based Idylla™ KRAS Mutation Assay for Rapid KRAS Mutation Status Determination on Formalin-Fixed Paraffin-Embedded Tissue of Human Colorectal Cancer

Jérôme Solassol, Julie A. Vendrell, Bruno Märkl, +22

PLoS ONE

ImmunologyPathologyOncologyGastrointestinal OncologyMulti-center Evaluation +16

Mitogen-activated protein kinase phosphatase-1 (MKP-1) impairs the response to anti-epidermal growth factor receptor (EGFR) antibody cetuximab in metastatic colorectal cancer patients

Clara Montagut, Mar Iglesias, Montserrat Arumí, +13

British Journal of Cancer

FCGR polymorphisms and cetuximab efficacy in chemorefractory metastatic colorectal cancer: an international consortium study

Ravit Geva, Loredana Vecchione, Konstantinos T Kalogeras, +26

Gut