Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells

Keqiang Ye, Yong Ke, Nagalakshmi Keshava, +5

Proceedings of the National Academy of Sciences

Cell DeathPharmacotherapyOpium Alkaloid NoscapineTumor BiologyMedicinal Chemistry +14

Gamma delta T lymphocytes regulate the induction and maintenance of oral tolerance

Yong Ke, KEVIN M. PEARCE, J P Lake, +2

The Journal of Immunology

Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses

Yong Ke, Keqiang Ye, Hans E. Grossniklaus, +3

Cancer Immunology Immunotherapy

Normal TissuesChemoprevention StrategyMedicineTumor GrowthImmunology +10

Exogenous antigens gain access to the major histocompatibility complex class I processing pathway in B cells by receptor-mediated uptake.

Yong Ke, Judith A. Kapp

The Journal of Experimental Medicine

HistocompatibilityExogenous AntigensHla ImmunogeneticsImmunologyImmunodominance +20

Oral antigen inhibits priming of CD8+ CTL, CD4+ T cells, and antibody responses while activating CD8+ suppressor T cells

Yong Ke, Judith A. Kapp

The Journal of Immunology

Ovalbumin injected with complete Freund's adjuvant stimulates cytolytic responses

Yong Ke, Ying Li, Judith A. Kapp

European Journal of Immunology

ImmunologyImmunologic MechanismAntigen ProcessingPharmacotherapyCd4 T Cell Responses +16

Secretion of IL-2 and IFN-γ, But Not IL-4, by Antigen-Specific T Cells Requires Extracellular ATP

Heather P. Langston, Yong Ke, Andrew T. Gewirtz, +2

The Journal of Immunology

Antigen Is Required for the Activation of Effector Activities, whereas Interleukin 2 Is Required for the Maintenance of Memory in Ovalbumin-specific, CD8+ Cytotoxic T Lymphocytes

Yong Ke, Hak‐Ling Ma, Judith A. Kapp

The Journal of Experimental Medicine

Single Chain Fragment Variable (scFv) Antibodies Targeting the Spike Protein of Porcine Epidemic Diarrhea Virus Provide Protection against Viral Infection in Piglets

Fanqing Zhang, Yuxue Chen, Yong Ke, +4

Viruses

Spike ProteinMedicinePathogenesisViral PathogenesisImmunology +11

Antigen recognition by CTL is dependent upon ectoATPase activity.

Kenneth E. Dombrowski, Yong Ke, L. Thompson, +1

The Journal of Immunology

Signal TransductionBiochemistryNatural SciencesCtl EctoatpaseBenzoyl Adenosine +13