A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo

Helena Soares, HaeNa Waechter, Nicholas Glaichenhaus, +6

The Journal of Experimental Medicine

The microbial mimic poly IC induces durable and protective CD4⁺T cell immunity together with a dendritic cell targeted vaccine

Christine Trumpfheller, Marina Caskey, Godwin Nchinda, +6

Proceedings of the National Academy of Sciences

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

Godwin Nchinda, Janelle Kuroiwa, Margarita Oks, +9

Journal of Clinical Investigation

ImmunologyImmunodominanceImmunotherapyVaccine AntigenCross-protection +17

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

Keith Levendosky, Olga Mizenina, Elena Martinelli, +9

Antimicrobial Agents and Chemotherapy

Carrageenan CombinationGlycobiologyImmunologyPathologyAnalytical Ultracentrifugation +18

Classical Flt3L-dependent dendritic cells control immunity to protein vaccine

Niroshana Anandasabapathy, Rachel Feder, Shamim Mollah, +15

The Journal of Experimental Medicine

Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

Nina Derby, Manjari Lal, Meropi Aravantinou, +23

Nature Communications

A novel intravaginal ring to prevent HIV-1, HSV-2, HPV, and unintended pregnancy

Shweta R. Ugaonkar, Asa Wesenberg, Wilk Jolanta, +17

Journal of Controlled Release

In vitro and in vivo evaluation of two carrageenan-based formulations to prevent HPV acquisition

Aixa Rodríguez, Kyle Kleinbeck, Olga Mizenina, +11

Antiviral Research

Carrageenan-based FormulationsImmunologyCg FormulationsHpv InfectionAntiviral Drug +14

An IFN-γ-IL-18 Signaling Loop Accelerates Memory CD8+ T Cell Proliferation

Yoshiko Iwai, Hiroaki Hemmi, Olga Mizenina, +3

PLoS ONE

Adaptive Immune SystemT-regulatory CellImmune RegulationImmunologyImmunologic Mechanism +16

A Potent Combination Microbicide that Targets SHIV-RT, HSV-2 and HPV

Larisa Kizima, Aixa Rodríguez, Jessica Kenney, +19

PLoS ONE