Richard B. Rothman

High affinity dopamine reuptake inhibitors as potential cocaine antagonists: A strategy for drug development

Richard B. Rothman · Life Sciences · 1990 · 127 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Alterations in the stereochemistry of the .kappa.-selective opioid agonist U50,488 result in high-affinity .sigma. ligands

Brian R. de Costa, W. Don Bowen, Susan B. Hellewell et al. · Journal of Medicinal Chemistry · 1989 · 73 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Opioid peptide receptor studies, 11: Involvement of Tyr148, Trp318 and His319 of the rat ?-opioid receptor in binding of ?-selective ligands

Heng Xu, Yifeng Lu, John S. Partilla et al. · Synapse · 1999 · 49 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Studies of the biogenic amine transporters. 1. Dopamine reuptake blockers inhibit [3H]mazindol binding to the dopamine transporter by a competitive mechanism: Preliminary evidence for different binding domains

Christina M. Dersch, Hyacinth C. Akunne, John S. Partilla et al. · Neurochemical Research · 1994 · 32 citations

Medicine, Neuroscience, Pharmacology +15

Probes for narcotic receptor mediated phenomena. 18. Epimeric 6.alpha.- and 6.beta.-iodo-3,14-dihydroxy-17-(cyclopropylmethyl)-4,5.alpha.-epoxymorphinans as potential ligands for opioid receptor single photon emission computed tomography: synthesis, evaluation, and radiochemistry of [125I]-6.beta.-iodo-3,14-dihydroxy-17-(cyclopropylmethyl)-4,5.alpha.-epoxymorphinan

Brian R. de Costa, Michael J. Iadarola, Richard B. Rothman et al. · Journal of Medicinal Chemistry · 1992 · 29 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17