Sara Chaffee

High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors.

Michael L. Graham, James E. Herndon, Joseph R. Casey et al. · Journal of Clinical Oncology · 1997 · 172 citations

Medicine, Oncology, Pharmacology +17

Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury

Fabio Silvio Taccone, Carla Bittencourt Rynkowski, Kirsten Møller et al. · JAMA · 2024 · 145 citations · Full text

Medicine, Hematology, Neurosurgery +16

IgG antibody response to polyethylene glycol-modified adenosine deaminase in patients with adenosine deaminase deficiency.

Sara Chaffee, Ann Mary, E. Richard Stiehm et al. · Journal of Clinical Investigation · 1992 · 113 citations · Full text

Life Sciences, Immunology, Pharmacotherapy +15

Use of site-directed mutagenesis to enhance the epitope-shielding effect of covalent modification of proteins with polyethylene glycol.

M S Hershfield, Sara Chaffee, Lillian Koro-Johnson et al. · Proceedings of the National Academy of Sciences · 1991 · 105 citations

Life Sciences, Biochemistry, Biotechnology +17

Enzyme Replacement Therapy with Polyethylene Glycol-Adenosine Deaminase in Adenosine Deaminase Deficiency: Overview and Case Reports of Three Patients, Including Two Now Receiving Gene Therapy

Michael S. Hershfield, Sara Chaffee, Ricardo U. Sorensen · Pediatric Research · 1993 · 69 citations

Life Sciences, Biochemistry, Molecular Biology +11