Withaferin A Causes FOXO3a- and Bim-Dependent Apoptosis and Inhibits Growth of Human Breast Cancer Cells <i>In vivo</i>

Silvia D. Stan, Eun-Ryeong Hahm, Renaud Warin, +1

Cancer Research

Sulforaphane Inhibits Prostate Carcinogenesis and Pulmonary Metastasis in TRAMP Mice in Association with Increased Cytotoxicity of Natural Killer Cells

Shivendra V. Singh, Renaud Warin, Dong Xiao, +12

Cancer Research

UrologyOncologyChemoprevention StrategyOncogenic AgentMedicine +12

Garlic Constituent Diallyl Trisulfide Prevents Development of Poorly Differentiated Prostate Cancer and Pulmonary Metastasis Multiplicity in TRAMP Mice

Shivendra V. Singh, Anna A. Powolny, Silvia D. Stan, +8

Cancer Research

Metabolism of [6]-Shogaol in Mice and in Cancer Cells

Huadong Chen, Lishuang Lv, Dominique N. Soroka, +6

Drug Metabolism and Disposition

Prevention of Mammary Carcinogenesis in MMTV-<i>neu</i>Mice by Cruciferous Vegetable Constituent Benzyl Isothiocyanate

Renaud Warin, William H. Chambers, Douglas M. Potter, +1

Cancer Research

Inhibition of human breast cancer xenograft growth by cruciferous vegetable constituent benzyl isothiocyanate

Renaud Warin, Dong Xiao, Julie A. Arlotti, +2

Molecular Carcinogenesis

Cysteine-Conjugated Metabolites of Ginger Components, Shogaols, Induce Apoptosis through Oxidative Stress-Mediated p53 Pathway in Human Colon Cancer Cells

Junsheng Fu, Huadong Chen, Dominique N. Soroka, +2

Journal of Agricultural and Food Chemistry

Chemoprevention StrategyLipid PeroxidationGinger ComponentsCell DeathRedox Biology +18

Metabolites of Ginger Component [6]-Shogaol Remain Bioactive in Cancer Cells and Have Low Toxicity in Normal Cells: Chemical Synthesis and Biological Evaluation

Yingdong Zhu, Renaud Warin, Dominique N. Soroka, +2

PLoS ONE

Induction of Lung Cancer Cell Apoptosis through a p53 Pathway by [6]-Shogaol and Its Cysteine-Conjugated Metabolite M2

Renaud Warin, Huadong Chen, Dominique N. Soroka, +2

Journal of Agricultural and Food Chemistry

Chemoprevention StrategyLipid PeroxidationApoptosisCell DeathCysteine-conjugated Metabolite M2 +15

Erythropoietin signaling promotes transplanted progenitor cell survival

Yi Jia, Renaud Warin, Xiaobing Yu, +2

The FASEB Journal

Cell DeathCellular PhysiologyRegenerative MedicineSignaling PathwayStem Cell Transplantation +16