The inhibitory effect of vitamin K2 (Menatetrenone) on bone resorption may be related to its side chain

Kuniko Hara, Yasuhiro Akiyama, Tetsuya Nakamura, +2

Bone

Bone HealthBone ResorptionVitamin K2MedicinePhysiology +9

Menatetrenone inhibits bone resorption partly through inhibition of PGE2 synthesis in vitro

Kuniko Hara, Yasuhiro Akiyama, Tetsuya Tajima, +1

Journal of Bone and Mineral Research

Pge2 ProductionSclerostinPge2 SynthesisBone ResorptionOsteoporosis +14

Effect of vitamin K2 (menatetrenone) on osteoclast-like cell formation in mouse bone marrow cultures

Yasuhiro Akiyama, Kuniko Hara, Tetsuya Tajima, +2

European Journal of Pharmacology

Developmental BiologyBone Morphogenic ProteinVitamin K2OsteoporosisOsteoclast-like Cell Formation +5

Effects of menatetrenone on prednisolone-induced bone loss in rats

Kuniko Hara, Yasuhiro Akiyama, Isao Ohkawa, +1

Bone

MedicinePrednisolone-induced Bone LossOsteoarthritisBone HomeostasisEndocrinology +4

Vitamin K2 (menatetrenone) inhibits bone loss induced by prednisolone partly through enhancement of bone formation in rats

Kuniko Hara, Masakazu Kobayashi, Yasuhiro Akiyama

Bone

Bone LossVitamin K2MedicinePhysiologyOsteoarthritis +8

Enhanced production of nitric oxide may be involved in acute hypotension during maintenance hemodialysis

Masaharu Nishimura, Hidenori Takahashi, Katsuya Maruyama, +4

American Journal of Kidney Diseases

HemodialysisUrologyRenal FunctionEnhanced ProductionNitrosative Stress +8

Circulating Levels and Bone Contents of Bone γ-Carboxyglutamic Acid-Containing Protein Are Decreased in Streptozocin-Induced Diabetes: Possible Marker for Diabetic Osteopenia

Hitoshi Ishida, Yutaka Seino, Tomohiko Taminato, +8

Diabetes

Effects of vitamin K2 (menatetrenone) and alendronate on bone mineral density and bone strength in rats fed a low-magnesium diet

Masakazu Kobayashi, Kuniko Hara, Yasuhiro Akiyama

Bone

NutritionBone HealthBody CompositionVitamin K2Medicine +10

Comparison of intestinal absorption of vitamin K2 (menaquinone) homologues and their effects on blood coagulation in rats with hypoprothrombinaemia

Yasuhiro Akiyama, Kuniko Hara, Akira Matsumoto, +2

Biochemical Pharmacology

Vitamin K AntagonistsNutritionNutrient PhysiologyHealth SciencesVitamin K2 +8

Increased circulating levels of γ-carboxyglutamic acid-containing protein and decreased bone mass in children on anticonvulsant therapy

Noritaka Takeshita, Yutaka Seino, Hitoshi Ishida, +10

Calcified Tissue International

Circulating LevelsHealth SciencesMedicineClinical NutritionHematology +5