Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity

Dehe Kong, Eun‐Jung Park, Andrew G. Stephen, +6

Cancer Research

Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability.

A. Steven Fleisher, Manel Esteller, Suna Wang, +14

PubMed

Epigenetic ChangeGeneticsPathologyCancer BiologyEpigenetics +18

Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia

Takashi Tsuchiya, Gen Tamura, Kiyoshi Sato, +15

Oncogene

ChromatinCancerous Gastric EpitheliaDistinct Methylation PatternsEpigenetic ChangeGenetics +9

Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia

A. Steven Fleisher, Manel Esteller, Gen Tamura, +11

Oncogene

Hmlh1 Gene PromoterSomatic VariantGenetic DisorderEpigenetic ChangeGenetics +6

Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells

Rhonda F Souza, Suna Wang, Manjusha Thakar, +7

Oncogene

Tumor BiologyColorectal Carcinoma CellsMedicineColorectal CancerPathology +5

Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas

Jing Yin, Dehe Kong, Suna Wang, +10

Human Mutation

Tumor BiologyGenome InstabilityNormal Protein FunctionMicrosatellite SequencesSomatic Variant +11

"Vasocrine" formation of tumor cell-lined vascular spaces: implications for rational design of antiangiogenic therapies.

Susanna M. Rybak, Elena Sanovich, Melinda G. Hollingshead, +6

PubMed

Antiangiogenic TherapiesImmunologyBiomedical EngineeringTumor BiologyIcrf 159 +15

Targeting the PAS-A Domain of HIF-1α for Development of Small Molecule Inhibitors of HIF-1

Jung‐Eun Park, Dehe Kong, Robert J. Fisher, +3

Cell Cycle

Modulation of Aldehyde Dehydrogenase Activity Affects (±)-4-Hydroxy-2E-nonenal (HNE) Toxicity and HNE–Protein Adduct Levels in PC12 Cells

Dehe Kong, Vinayaka Kotraiah

Journal of Molecular Neuroscience

Redox SignalingPc12 CellsAldehyde DehydrogenaseBiochemistryNatural Sciences +11

Identification of aldehyde dehydrogenase 1A1 modulators using virtual screening

Vinayaka Kotraiah, Diego Pallares, Deanna Toema, +2

Journal of Enzyme Inhibition and Medicinal Chemistry

Aldo-keto ReductaseAldh1a1 MrnaAldehyde Dehydrogenase 1A1Neurochemical BiomarkersChemical Biology +16