Young-Mo Seong

Alzheimer's disease-associated amyloid beta interacts with the human serine protease HtrA2/Omi

Hyojin Park, Young-Mo Seong, Ju-Youn Choi et al. · Neuroscience Letters · 2004 · 67 citations

Molecular Neuroscience, Alzheimer's Disease, Biochemistry +10

Autocatalytic Processing of HtrA2/Omi Is Essential for Induction of Caspase-dependent Cell Death through Antagonizing XIAP

Young-Mo Seong, Ju-Youn Choi, Hyojin Park et al. · Journal of Biological Chemistry · 2004 · 47 citations · Full text

Autocatalytic Processing, Mitophagy, Apoptosis Protein +17

The homotrimeric structure of HtrA2 is indispensable for executing its serine protease activity

Min-Kyung Nam, Young-Mo Seong, Hyojin Park et al. · Experimental & Molecular Medicine · 2006 · 17 citations · Full text

Protein Chemistry, Protein Function, Protein Assembly +13

N-terminal truncation circumvents proteolytic degradation of the human HtrA2/Omi serine protease in Escherichia coli: rapid purification of a proteolytically active HtrA2/Omi

Young-Mo Seong, Hyojin Park, Geun-Hye Seong et al. · Protein Expression and Purification · 2003 · 15 citations

Protein Expression, Biochemistry, Medicine +10