B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4

Gordon J. Freeman, Vassiliki A. Boussiotis, Anukanth Anumanthan, +6

Immunity

Initial ProductionImmunologyAutoimmunitySystems BiologyMedicine +1

Expression of myeloid differentiation antigens on normal and malignant myeloid cells.

James D. Griffin, Jerome Ritz, L M Nadler, +1

Journal of Clinical Investigation

Mixed-phenotype Acute LeukemiaImmunologyPathologyMalignant Myeloid CellsImmunotherapy +14

B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells.

Gordon J. Freeman, Arnold S. Freedman, J Segil, +3

The Journal of Immunology

CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy.

Joachim L. Schultze, S. Michalak, Mark J. Seamon, +6

Journal of Clinical Investigation

Cell TherapyAdaptive Immune SystemImmunologyAntigen ProcessingCd4 T Cell Responses +16

Characterization of CTLA-4 structure and expression on human T cells.

Tullia Lindsten, K P Lee, Estelle S. Harris, +7

The Journal of Immunology

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

Dimitrios Tzachanis, Gordon J. Freeman, Naoto Hirano, +5

Nature Immunology

Signal TransductionNegative RegulatorT-regulatory CellImmunologyCellular Regulatory Mechanism +7

Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules.

Sivasubramanian Baskar, Suzanne Ostrand‐Rosenberg, N Nabavi, +3

Proceedings of the National Academy of Sciences

HistocompatibilityResident Tumor CellsT-regulatory CellImmunologyImmunologic Mechanism +17

Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation.

Kathryn T. Hall, Laurence Boumsell, Joachim L. Schultze, +6

Proceedings of the National Academy of Sciences

Lymphocyte DevelopmentAdaptive Immune SystemImmune RegulationImmunologyBlood Cell +20

The B cell surface molecule B1 is functionally linked with B cell activation and differentiation.

Thomas F. Tedder, A W Boyd, AS Freedman, +2

The Journal of Immunology

Follicular lymphomas can be induced to present alloantigen efficiently: a conceptual model to improve their tumor immunogenicity.

Joachim L. Schultze, Angelo A. Cardoso, Gordon J. Freeman, +5

Proceedings of the National Academy of Sciences

ImmunologyAntigen ProcessingConceptual ModelT CellsImmunotherapy +16