Reduced Activation of Phosphatidylinositol-3 Kinase and Increased Serine 636 Phosphorylation of Insulin Receptor Substrate-1 in Primary Culture of Skeletal Muscle Cells From Patients With Type 2 Diabetes

Karim Bouzakri, Marina Roques, Philippe Gual, +7

Diabetes

Skeletal Muscle CellsInsulin SignalingCellular PhysiologyMetabolic SyndromeSkeletal Muscle +18

Triiodothyronine‐mediated upregulation of UCP2 and UCP3 mRNA expression in human skeletal muscle without coordinated induction of mitochondrial respiratory chain genes

P Barbe, Dominique Larrouy, Catherine Boulanger, +7

The FASEB Journal

Muscle FunctionMitochondrial BiologyCellular PhysiologyOxidative StressTranscriptional Regulation +23

The Regulation of Uncoupling Protein-2 Gene Expression by ω-6 Polyunsaturated Fatty Acids in Human Skeletal Muscle Cells Involves Multiple Pathways, Including the Nuclear Receptor Peroxisome Proliferator-activated Receptor β

Emmanuel Chevillotte, Jennifer Rieusset, Marina Roques, +2

Journal of Biological Chemistry

Cellular PhysiologyProtein-2 Gene ExpressionTranscriptional RegulationSkeletal MuscleFatty Acids +17

Sterol Regulatory Element-Binding Protein-1 Mediates the Effect of Insulin on Hexokinase II Gene Expression in Human Muscle Cells

Yvan Gosmain, Étienne Lefai, Stephan Ryser, +2

Diabetes

A Phosphatidylinositol 3-Kinase/p70 Ribosomal S6 Protein Kinase Pathway Is Required for the Regulation by Insulin of the p85α Regulatory Subunit of Phosphatidylinositol 3-Kinase Gene Expression in Human Muscle Cells

Marina Roques, Hubert Vidal

Journal of Biological Chemistry

Expression of the splice variants of the p85α regulatory subunit of phosphoinositide 3-kinase in muscle and adipose tissue of healthy subjects and type 2 diabetic patients

Étienne Lefai, Marina Roques, Nathalie Véga, +2

Biochemical Journal

Healthy SubjectsInsulin SignalingMetabolic SyndromeSkeletal MuscleSplice Variants +20

Regulation of p85α phosphatidylinositol‐3‐kinase expression by peroxisome proliferator‐activated receptors (PPARs) in human muscle cells

Jennifer Rieusset, Marina Roques, Karim Bouzakri, +2

FEBS Letters

Encapsulation of Insulin for Oral Administration Preserves Interaction of the Hormone with Its Receptor In Vitro

Marina Roques, Christiane Damgé, Christine Michel, +3

Diabetes

Signal TransductionBiochemistryHuman Insulin ReceptorNative InsulinDiabetes +10

Expression of arylhydrocarbon hydroxylase, epoxide hydrolases, glutathione S-transferase and UDP-glucuronosyltransferases in H5-6 hepatoma cells

Marina Roques, Denyse Bagrel, Jacques Magdalou, +1

General Pharmacology The Vascular System

BiosynthesisCellular EnzymologyBiochemistryLiver PhysiologyEpoxide Hydrolases +8