Assays related to cancer drug discovery

M Suffness, JM Pezzuto

Medical Entomology and Zoology

Drug TargetOncologyMedicineAnti-cancer AgentDrug Development +4

Taxol®: science and applications.

M Suffness, Monroe E. Wall, H. R. Hartzell, +27

DerivativesMedicineFine ChemicalDrug DevelopmentPharmacology

A blind comparison of simple bench‐top bioassays and human tumour cell cytotoxicities as antitumor prescreens

J. E. Anderson, Christian Goetz, Jerry L. McLaughlin, +1

Phytochemical Analysis

Potato Disc AssaysPotato Disc AssayChemoprevention StrategyBlind ComparisonPathology +15

Synthesis of congeners and prodrugs. 3. Water-soluble prodrugs of taxol with potent antitumor activity

Howard M. Deutsch, Jan A. Gliński, M. Hernández, +4

Journal of Medicinal Chemistry

A reassessment of cardiac toxicity associated with Taxol.

Susan G. Arbuck, H. William Strausś, Eric K. Rowinsky, +7

PubMed

OncologyChemoprevention StrategyCardiovascular DiseaseMedicineCardiovascular Pharmacology +11

Bruceantin, a potent amoebicide from a plant, Brucea antidysenterica

Frances D. Gillin, David S. Reiner, M Suffness

Antimicrobial Agents and Chemotherapy

Medicinal ChemistryAmoebicidal ActivityAntiparasitic AgentMedicineAntibacterial Agent +10

Plants as sources of antimalarial drugs: in vitro antimalarial activities of some quassinoids

Melanie J. O’Neill, Dorothy Bray, Peter Boardman, +4

Antimicrobial Agents and Chemotherapy

PhytoalexinMedicinal ChemistryAntiparasitic AgentMedicineMalaria +13

Clinical development of Taxol.

Susan G. Arbuck, Michaele C. Christian, Jason S. Fisherman, +7

PubMed

Stable Microtubule BundlesPhase Ii EvaluationOncologyMedicineClinical Development +10

Antitumor activity and biochemical effects of aphidicolin glycinate (NSC 303812) alone and in combination with cisplatin in vivo.

P J O'Dwyer, James D. Moyer, M Suffness, +4

PubMed

Multiple InjectionsAntitumor ActivityGlycobiologyPharmacotherapyMetronomic Chemotherapy +15

Plants as a source of antimalarial drugs 5. Activities of <i>Ailanthus altissima</i> stem constituents and of some related quassinoids

Dorothy Bray, Peter Boardman, Melanie J. O’Neill, +4

Phytotherapy Research

Medicinal ChemistryAntimalarial Drugs 5Related QuassinoidsAllergyBotany +13