Isolation and structural elucidation of new cyclotetrapeptides, trapoxins A and B, having detransformation activities as antitumor agents.

Hiroshi Itazaki, K. Nagashima, Kenji Sugita, +11

The Journal of Antibiotics

(2S,3S,4S) α-(Carboxycyclopropyl) glycine is a novel agonist of metabotropic glutamate receptors

Yuzo NAKAGAWA, Kyoshi Saitoh, Takafumi Ishihara, +2

European Journal of Pharmacology

Metabotropic Glutamate ReceptorsBiochemistryG Protein-coupled ReceptorMedicineSynaptic Transmission +5

OPTICAL ISOMERIZATION MECHANISM OF R (-)-HYDRATROPIC ACID DERIVATIVES

Yutaka Nakamura, Toshiro Yamaguchi, Shirō Takahashi, +3

Journal of Pharmacobio-Dynamics

Acid DerivativesDerivative (Chemistry)PhotochemistryOrganic ChemistryChemistry +1

Chemical studies on crude drug processing. VI. Chemical structures of malonyl-ginsenosides Rb1, Rb2, Rc, and Rd isolated from the root of Panax ginseng C.A. Meyer.

Isao Kitagawa, TOSHIO TANIYAMA, Masayuki Yoshikawa, +2

Chemical and Pharmaceutical Bulletin

Malonyl-ginsenosides Rb1Pharmaceutical ChemistryPharmaceutical ScienceBiochemistryBioassay-guided Isolation +12

Colchicine lesions in the rat hippocampus mimic the alterations of several markers in Alzheimer's disease

Yuzo NAKAGAWA, Shizuo Nakamura, Yoshitoshi Kasé, +2

Brain Research

Rat HippocampusSeveral MarkersAlzheimer's DiseaseNeuroanatomyDementia +10

Structure of a new class of C-nucleoside antibiotic, showdomycin

Yuzo NAKAGAWA, Hideo Kanō, Y. Tsukuda, +1

Tetrahedron Letters

Medicinal ChemistryBioorganic ChemistryNatural SciencesMolecular BiologyNew Class +3

Intrahippocampal colchicine injection results in spectrin proteolysis

Peter Seubert, Yuzo NAKAGAWA, Gwen O. Ivy, +3

Neuroscience

OptogeneticsCellular NeurosciencePharmacologySpectrin ProteolysisNeuropeptides

Structures of new peptide antibiotics, plusbacins A1-A4 and B1-B4.

JUN''ICHI SHOJI, HIROSHI HINOO, Teruaki Katayama, +4

The Journal of Antibiotics

Chitinovorins A, B and C, novel .BETA.-lactam antibiotics of bacterial origin.

JUN''ICHI SHOJI, Toshiyuki Kato, RYUZI SAKAZAKI, +8

The Journal of Antibiotics

Antimicrobial Drug DiscoveryAntibioticsMedicineAntibacterial AgentAntimicrobial Chemotherapy +6

A single class of neurotensin receptors with high affinity in neuroblastoma X glioma NG108-15 hybrid cells that mediate facilitation of synaptic transmission

Yuzo NAKAGAWA, Haruhiro Higashida, Naomasa Miki

Journal of Neuroscience

Tumor InnervationSynaptic TransmissionDissociation ConstantNeurotensin BindingGlioma +16