Marianne Le Meur

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene

Hans W. D. Matthes, Rafaël Maldonado, Frédéric Simonin et al. · Nature · 1996 · 1.7K citations

Medicine, Neuroscience, Pharmacology +17

Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

Ja‐Hyun Baik, Roberto Picetti, Adolfo Saiardi et al. · Nature · 1995 · 648 citations

Life Sciences, Neurobiology, Neuroscience +14

Absence of integrin α6 leads to epidermolysis bullosa and neonatal death in mice

Elisabeth Georges‐Labouesse, Nadia Messaddeq, Ghassan Yehia et al. · Nature Genetics · 1996 · 541 citations

Life Sciences, Cell Biology, Molecular Biology +13

Disruption of the κ‐opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective κ‐agonist U‐50,488H and attenuates morphine withdrawal

Frédéric Simonin, Olga Valverde, Claire Smadja et al. · The EMBO Journal · 1998 · 413 citations

Medicine, Pharmacology, Molecular Pharmacology +16

Serotonin 2B receptor is required for heart development

Canan G. Nebigil, Doo‐Sup Choi, Andrée Dierich et al. · Proceedings of the National Academy of Sciences · 2000 · 363 citations

Life Sciences, Developmental Biology, Genetics +14