Pharmacokinetics and metabolism of epidoxorubicin and doxorubicin in humans.

K. Mross, Paul A. Maessen, W J van der Vijgh, +3

Journal of Clinical Oncology

Bolus InjectionMolecular PharmacologyMedicinal ChemistryPharmaceutical SciencePharmacokinetic Modeling +13

Pharmacokinetics of free and total platinum species after short-term infusion of cisplatin.

Jan B. Vermorken, W. J. F. van der Vijgh, I. Klein, +3

PubMed

Cstrip ApproachPhysiologically-based Pharmacokinetic ModelingMedicineExponential FunctionBioanalysis +12

Phase I and pharmacokinetic study of 5-aza-2'-deoxycytidine (NSC 127716) in cancer patients.

C.J. van Groeningen, A. Leyva, A.M.P. O'Brien, +2

PubMed

Pharmacokinetic StudyPharmacotherapyCancer PatientsAdvanced Solid TumorsHematological Malignancy +14

Phase I and pharmacokinetic studies of high-dose uridine intended for rescue from 5-fluorouracil toxicity.

A. Leyva, C.J. van Groeningen, I Kraal, +4

PubMed

Pharmacokinetic StudiesPharmaceutical ScienceUrology5-Fluorouracil ToxicityPharmacological Study +10

Pharmacokinetics of free platinum species following rapid, 3-hr and 24-hr infusions of cis-diamminedichloroplatinum (II) and its therapeutic implications

J. B. Vermorken, W. J. F. van der Vijgh, I. Klein, +2

European Journal of Cancer and Clinical Oncology

Free Platinum Species24-Hr InfusionsMedicinePharmacotherapyTherapeutic Implications +2

Skin tests predict survival after autologous tumor cell vaccination in metastatic melanoma: Experience in 81 patients

Arnold Baars, A.M.E. Claessen, A.J.M. van den Eertwegh, +9

Annals of Oncology

VaccinationTumor ImmunologyCancer ImmunosurveillanceMedicineSkin Tests +8

Pharmacokinetics of carboplatin after i.v. administration.

F. Elferink, W J van der Vijgh, I. Klein, +3

PubMed

OncologyPharmacokinetic ModelingFinal Half-lifeMedicineFree Pt +10

Pharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors

Godefridus J. Peters, Paul Noordhuis, André B. P. Kuilenburg, +12

Cancer Chemotherapy and Pharmacology

Solid TumorsMedicinePharmacologyMolar Ratio 1:0.4:1Pharmacotherapy +7

Pharmacokinetics and pharmacodynamics of lobaplatin (D-19466) in patients with advanced solid tumors, including patients with impaired renal of liver function.

Jan Welink, E. Boven, Jan B. Vermorken, +2

PubMed

PharmacotherapyLiver FunctionMetronomic ChemotherapyAdvanced Solid TumorsHematological Malignancy +14

Influence of amifostine on the pharmacokinetics of cisplatin in cancer patients.

A.E.C. Korst, M L van der Sterre, H.E. Gall, +3

PubMed

Serum Creatinine LevelsMolecular PharmacologyTherapeutic Drug MonitoringUrologyOncology +10