Generation of Plasma Cells From Peripheral Blood Memory B Cells: Synergistic Effect of Interleukin-10 and CD27/CD70 Interaction

Kazunaga Agematsu, Haruo Nagumo, Yumiko Oguchi, +7

Blood

Absence of IgD-CD27(+) memory B cell population in X-linked hyper-IgM syndrome.

Kazunaga Agematsu, Haruo Nagumo, Koji Shinozaki, +8

Journal of Clinical Investigation

InflammationImmunological MemoryImmunoglobulin ReceptorsAutoimmune DiseaseImmunodeficiencies +12

Theophylline accelerates human granulocyte apoptosis not via phosphodiesterase inhibition.

Kozo Yasui, Bao‐Shan Hu, T Nakazawa, +2

Journal of Clinical Investigation

AsthmaApoptosisImmunologyCell DeathCellular Physiology +15

Successful Treatment of Behcet Disease with Pentoxifylline

Kozo Yasui

Annals of Internal Medicine

ImmunodeficienciesImmunologyPathologyBehçet DiseasebehçetPharmacotherapy +23

Theophylline induces neutrophil apoptosis through adenosine A2A receptor antagonism

Kozo Yasui, Kazunaga Agematsu, Koji Shinozaki, +4

Journal of Leukocyte Biology

ApoptosisImmunologyCell DeathPharmacotherapyReceptor Antagonism +15

CD27/CD70 Interaction Augments IgE Secretion by Promoting the Differentiation of Memory B Cells into Plasma Cells

Haruo Nagumo, Kazunaga Agematsu, Koji Shinozaki, +8

The Journal of Immunology

Signal TransductionPlasma CellsB Cell ProliferationImmunologyImmune Regulation +13

ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils

Masaaki Shiohara, S. Taniguchi, Junya Masumoto, +4

Biochemical and Biophysical Research Communications

InflammationAnti-inflammatoryGranulocyteHuman NeutrophilsImmunology +9

Thalidomide dramatically improves the symptoms of early‐onset Sarcoidosis/Blau syndrome: Its possible action and mechanism

Kozo Yasui, Masato Yashiro, Mitsuru Tsuge, +4

Arthritis & Rheumatism

Signal transduction pathway in human polymorphonuclear leukocytes for chemotaxis induced by a chemotactic factor. Distinct from the pathway for superoxide anion production.

Kozo Yasui, Munehiro Yamazaki, M Miyabayashi, +2

The Journal of Immunology

Anakinra improves sensory deafness in a Japanese patient with Muckle‐Wells syndrome, possibly by inhibiting the cryopyrin inflammasome

Takashi Yamazaki, Junya Masumoto, Kazunaga Agematsu, +5

Arthritis & Rheumatism

Muckle-wells SyndromeClinical SymptomsImmunodeficienciesImmunologyPathology +16