Ada Girnita

The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway

Daiana Vasilcanu, Ada Girnita, Leonard Girnita et al. · Oncogene · 2004 · 151 citations

Tyrosine Phosphorylation, Insulin Signaling, Signal Transduction +12

RETRACTED ARTICLE:Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor

Ada Girnita, Huiyuan Zheng, Alvar Grönberg et al. · Oncogene · 2011 · 84 citations · Full text

Immunology, Cell Death, Pathology +24

Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and β-arrestin1

Radu Vasilcanu, D. Vasilcanu, Lars Rosengren et al. · Oncogene · 2007 · 73 citations

Molecular Pharmacology, Potential Mechanistic Involvement, Molecular Physiology +10

Oral Picropodophyllin (PPP) Is Well Tolerated In Vivo and Inhibits IGF-1R Expression and Growth of Uveal Melanoma

Mario A. Economou, Sandra Andersson, D. Vasilcanu et al. · Investigative Ophthalmology & Visual Science · 2008 · 54 citations

The insulin-like growth factor-1 receptor inhibitor PPP produces only very limited resistance in tumor cells exposed to long-term selection

D. Vasilcanu, W-H Weng, Ada Girnita et al. · Oncogene · 2005 · 48 citations

Cancer Research, Growth Hormone, Limited Resistance +10