D Falb

Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress.

James N. Topper, Jiexing Cai, D Falb et al. · Proceedings of the National Academy of Sciences · 1996 · 838 citations · Full text

Turbulent Shear Stress, Vascular Disease, Engineering +21

The TGF-β signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer

Jörg Kleeff, Toshiyuki Ishiwata, Haruhisa Maruyama et al. · Oncogene · 1999 · 258 citations

Pancreatic Cancer, Medicine, Cancer Cell Biology +7

A conserved regulatory unit implicated in tissue-specific gene expression in Drosophila and man.

D Falb, Tom Maniatis · Genes & Development · 1992 · 85 citations · Full text

Genetics, Molecular Genetics, Gene Regulatory Network +16

Expression of the bumetanide-sensitive Na-K-Cl cotransporter BSC2 is differentially regulated by fluid mechanical and inflammatory cytokine stimuli in vascular endothelium.

James N. Topper, Scott M. Wasserman, Keith R. Anderson et al. · Journal of Clinical Investigation · 1997 · 62 citations · Full text

Drosophila transcriptional repressor protein that binds specifically to negative control elements in fat body enhancers.

D Falb, Tom Maniatis · Molecular and Cellular Biology · 1992 · 48 citations · Full text

Transcriptional Regulation, Systems Biology, Developmental Biology +10