Klaus-Peter Kuenkele

R1507, a Monoclonal Antibody to the Insulin-Like Growth Factor 1 Receptor, in Patients With Recurrent or Refractory Ewing Sarcoma Family of Tumors: Results of a Phase II Sarcoma Alliance for Research Through Collaboration Study

Alberto S. Pappo, Shreyaskumar Patel, John Crowley et al. · Journal of Clinical Oncology · 2011 · 321 citations

Medicine, Oncology, Immunotherapy +16

Structural Basis for the Regulation of Insulin-like Growth Factors by IGF Binding Proteins

Igor Siwanowicz, Grzegorz M. Popowicz, M. Wisniewska et al. · Structure · 2005 · 84 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Development of tetravalent IgG1 dual targeting IGF-1R–EGFR antibodies with potent tumor inhibition

Rebecca Croasdale, Katharina Wartha, Juergen Schanzer et al. · Archives of Biochemistry and Biophysics · 2012 · 47 citations

Medicine, Cancer Biology, Oncology +13

R1507, an Anti-Insulin-Like Growth Factor-1 Receptor (IGF-1R) Antibody, and EWS/FLI-1 siRNA in Ewing's Sarcoma: Convergence at the IGF/IGFR/Akt Axis

Helen J. Huang, Laura S. Angelo, Jordi Rodón et al. · PLoS ONE · 2011 · 39 citations · Full text

Medicine, Cancer Biology, Oncology +10