2, 3, 7, 8-Tetrachlorodibenzo-P-Dioxin (TCDD) Induces Premature Senescence in Human and Rodent Neuronal Cells via ROS-Dependent Mechanisms

Chunhua Wan, Jiao Liu, Xiaoke Nie, +6

PLoS ONE

AgingTcdd ExposureApparent Premature SenescenceCell DeathRedox Biology +17

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces microglial nitric oxide production and subsequent rat primary cortical neuron apoptosis through p38/JNK MAPK pathway

Yuanye Li, Gang Chen, Jianya Zhao, +5

Toxicology

InflammationP38/jnk Mapk PathwayMedicineApoptosisPharmacology +11

Pivotal roles of p53 transcription-dependent and -independent pathways in manganese-induced mitochondrial dysfunction and neuronal apoptosis

Chunhua Wan, Xa Ma, Shangshi Shi, +7

Toxicology and Applied Pharmacology

-Independent PathwaysMitophagyBiochemistryMitochondrial FunctionApoptosis +7

PFOS facilitates liver inflammation and steatosis: An involvement of NLRP3 inflammasome‐mediated hepatocyte pyroptosis

Yi Qin, Tianye Gu, Junyi Ling, +6

Journal of Applied Toxicology

ROS-mediated apoptosis of HAPI microglia through p53 signaling following PFOS exposure

Jianbin Ge, Cheng Wang, Xiaoke Nie, +12

Environmental Toxicology and Pharmacology

InflammationMedicineApoptosisAutophagyImmunology +10

2, 3, 7, 8‐Tetrachlorodibenzo‐<i>p</i>‐dioxin induces premature senescence of astrocytes via WNT/β‐catenin signaling and ROS production

Xiaoke Nie, Lingwei Liang, Hanqing Xi, +8

Journal of Applied Toxicology

The PERK-eIF2α signaling pathway is involved in TCDD-induced ER stress in PC12 cells

Zhiqing Duan, Jianya Zhao, Xikang Fan, +6

NeuroToxicology

Pc12 CellsSignal TransductionSignaling PathwayCell RegulationStress +8

Involvement of dysregulated Wip1 in manganese-induced p53 signaling and neuronal apoptosis

Xia Ma, Jingling Han, Qiyun Wu, +8

Toxicology Letters

Dysregulated Wip1Molecular NeuroscienceSignal TransductionApoptosisAutophagy +10

Perfluorooctane sulfonate mediates microglial activation and secretion of TNF-α through Ca2+-dependent PKC-NF-кB signaling

Jianbin Yang, Cheng Wang, Xiaoke Nie, +11

International Immunopharmacology

InflammationAnti-inflammatorySignal TransductionMedicineCa2+-dependent Pkc-nf-кb Signaling +6

Perfluorooctane sulfonate promotes hepatic lipid accumulation and steatosis in high‐fat diet mice through AMP‐activated protein kinase/acetyl‐CoA carboxylase (AMPK/ACC) pathway

Junyi Ling, Lu Hua, Yi Qin, +3

Journal of Applied Toxicology

Lipid PeroxidationFatty Liver DiseaseOxidative StressMetabolic SyndromeSubchronic Pfos Exposure +15