Increased oxidative stress in lambs with increased pulmonary blood flow and pulmonary hypertension: role of NADPH oxidase and endothelial NO synthase

Albert Grobe, Sandra M. Wells, Eileen Benavidez, +4

American Journal of Physiology-Lung Cellular and Molecular Physiology

Nadph OxidaseLipid PeroxidationPulmonary HypertensionShunt LambsRedox Biology +20

Asymmetric Dimethylarginine Induces Oxidative and Nitrosative Stress in Murine Lung Epithelial Cells

Sandra M. Wells, Andrij Holian

American Journal of Respiratory Cell and Molecular Biology

Asymmetric dimethylarginine inhibits HSP90 activity in pulmonary arterial endothelial cells: role of mitochondrial dysfunction

Neetu Sud, Sandra M. Wells, Shruti Sharma, +3

American Journal of Physiology-Cell Physiology

Mitochondrial DysfunctionNitric OxideOxidative StressInflammationReactive Nitrogen Specie +15

Alterations in zinc homeostasis underlie endothelial cell death induced by oxidative stress from acute exposure to hydrogen peroxide

Dean A. Wiseman, Sandra M. Wells, Maryann Hubbard, +2

American Journal of Physiology-Lung Cellular and Molecular Physiology

Acute ExposureApoptosisLipid PeroxidationCell DeathRedox Biology +14

Elevated Asymmetric Dimethylarginine Alters Lung Function and Induces Collagen Deposition in Mice

Sandra M. Wells, Mary Buford, Christopher T. Migliaccio, +1

American Journal of Respiratory Cell and Molecular Biology

AsthmaInflammatory Lung DiseaseLung InflammationImmunologyLung Collagen Content +14

Endothelial response to stress from exogenous Zn²⁺ resembles that of NO-mediated nitrosative stress, and is protected by MT-1 overexpression

Dean A. Wiseman, Sandra M. Wells, Jason M. Wilham, +3

American Journal of Physiology-Cell Physiology

Asymmetric dimethylarginine potentiates lung inflammation in a mouse model of allergic asthma

Elizabeth B. Klein, Jason Weigel, Mary Buford, +2

American Journal of Physiology-Lung Cellular and Molecular Physiology

AsthmaInflammatory Lung DiseaseLung InflammationAllergy MedicineNitric Oxide +16

Acute Inhalation Exposure to Vaporized Methamphetamine Causes Lung Injury in Mice

Sandra M. Wells, Mary Buford, Sarah N. Braseth, +2

Inhalation Toxicology

Acute Lung InjuryAsthmaLung DepositionAllergyLung Inflammation +13

Treatment with the C5a receptor/CD88 antagonist PMX205 reduces inflammation in a murine model of allergic asthma

Elizabeth Staab, Sam D. Sanderson, Sandra M. Wells, +1

International Immunopharmacology

AsthmaInflammationAllergyAllergy MedicineMedicine +7

Acute Lung Injury-Induced Collagen Deposition is Associated with Elevated Asymmetric Dimethylarginine and Arginase Activity

Linda E. Sousse, Yusuke Yamamoto, Perenlei Enkhbaatar, +10

Shock

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationNitric OxideImmunology +15