Shruti Sharma

IFI16 is an innate immune sensor for intracellular DNA

Leonie Unterholzner, Sinéad E. Keating, Marcin Baran et al. · Nature Immunology · 2010 · 1.6K citations · Full text

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

Vijay Rathinam, Zhaozhao Jiang, Stephen N. Waggoner et al. · Nature Immunology · 2010 · 1.3K citations · Full text

Host Response, Aim2 Inflammasome, Cytosolic Bacteria +10

Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid

Joseph Conlon, Dara Burdette, Shruti Sharma et al. · The Journal of Immunology · 2013 · 413 citations · Full text

Multiple Cathepsins Promote Pro–IL-1β Synthesis and NLRP3-Mediated IL-1β Activation

Gregory M. Orlowski, Jeff D. Colbert, Shruti Sharma et al. · The Journal of Immunology · 2015 · 263 citations · Full text

Inflammation, Cytokine, Sterile Particles +14

Innate Immune Recognition of an AT-Rich Stem-Loop DNA Motif in the Plasmodium falciparum Genome

Shruti Sharma, Rosane B. DeOliveira, Parisa Kalantari et al. · Immunity · 2011 · 257 citations · Full text

Dna Sequencing, Functional Genomics, Natural Sciences +15