Recognition of bacterial glycosphingolipids by natural killer T cells

Yuki Kinjo, Douglass Wu, Gisen Kim, +7

Nature

PathogenesisImmunologyBacterial GlycosphingolipidsAntigen ProcessingMicrobiology +2

Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria

Yuki Kinjo, Emmanuel Tupin, Douglass Wu, +16

Nature Immunology

PathogenesisImmunologyAntigen ProcessingAutoimmunityT Cell Immunity +5

Small molecules targeting severe acute respiratory syndrome human coronavirus

Chung‐Yi Wu, Jia-Tsrong Jan, Shiou-Hwa Ma, +13

Proceedings of the National Academy of Sciences

Medicinal ChemistrySars VirusProtease InhibitorMedicineNatural Sciences +13

Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells

Douglass Wu, Guo‐wen Xing, Michael A. Poles, +9

Proceedings of the National Academy of Sciences

Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity

Dirk M. Zajonc, Igor Maricic, Douglass Wu, +5

The Journal of Experimental Medicine

Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant

Xiangming Li, Masakazu Fujio, Masakazu Imamura, +5

Proceedings of the National Academy of Sciences

EngineeringImmunologyImmune RegulationImmunodominanceImmunoediting +23

Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids

Ya‐Jen Chang, Jingrong Huang, Yi-Chien Tsai, +5

Proceedings of the National Academy of Sciences

Design of natural killer T cell activators: Structure and function of a microbial glycosphingolipid bound to mouse CD1d

Douglass Wu, Dirk M. Zajonc, Masakazu Fujio, +5

Proceedings of the National Academy of Sciences

Structure-Based Discovery of Glycolipids for CD1d-Mediated NKT Cell Activation:  Tuning the Adjuvant versus Immunosuppression Activity

Masakazu Fujio, Douglass Wu, Raquel García‐Navarro, +3

Journal of the American Chemical Society

Conserved and Heterogeneous Lipid Antigen Specificities of CD1d-Restricted NKT Cell Receptors

Manfred Brigl, Peter van den Elzen, Xiuxu Chen, +8

The Journal of Immunology